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ID: 23FE10CSE00091

Brain Tumor Segmentation Using Residual 3D U-Net on the BraTS 2020 Dataset

"BraTS 2020 based deep learning model for accurate brain tumor sub‑region segmentation with strong false positive suppression."

Problem Statement

Brain tumor MRI segmentation is difficult due to severe class imbalance, complex tumor shapes and high false positives. Manual segmentation is slow and subjective. We design a Residual 3D U‑Net model that improves stability, accuracy and clinical reliability.

Literature Review / Market Research

Analyzed U-Net, Attention U-Net, Transformer models, BraTumIA pipeline, and commercial tools like Siemens syngo.via and GE Edison. Most advanced models are complex and need large proprietary datasets.

Research Gap / Innovation

Existing academic models show unstable training and high false positives. Our work improves reliability using residual learning, Focal Tversky loss, and post-processing without increasing complexity.

System Methodology

Dataset / Input

BraTS 2020 Dataset (100 patients subset). Multi-modal MRI: T1, T1ce, T2, FLAIR. Patch size: 96×96×96 with normalization.

Model / Architecture

Baseline: 3D U-Net. Proposed: Residual 3D U-Net (ResUNet v2). Loss: Focal Tversky Loss. Training: Adam optimizer, cross-validation, post-processing using connected component filtering.

Live Execution

VIEW CODE / DEMO

Results & Analysis

Accuracy / Performance Enhancing Tumor Dice = 85%

ResUNet v2 improves Dice scores across all tumor regions. Enhancing tumor Dice reached ~0.83–0.85 with high precision and strong false positive suppression compared to baseline 3D U-Net.

Academic Credits

Project Guide

Dr. Amit Kumar Gupta

Team Member 1

Manasvi Walia

23FE10CSE00091